Dctn4 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Dctn4 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Protein Name: Dynactin Subunit 4 (p62)
Gene: DCTN4
UniProt ID: Q9UBW9
PDB ID: None
Molecular Weight: 62 kDa
Subcellular Localization: Cytoplasm, Axons
Protein Family: Dynactin complex
DCTN4 has a distinctive structure adapted for its function:
DCTN4 is a subunit of the dynactin complex involved in dynein-dynactin-mediated retrograde transport. It contributes to the recruitment of cargo and the processivity of dynein motor activity.
DCTN4 mutations may contribute to neurodegenerative disease susceptibility.
DCTN4 represents a potential therapeutic target:
Dctn4 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Dctn4 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.