Dctn3 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Dctn3 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Protein Name: Dynactin Subunit 3 (p24)
Gene: DCTN3
UniProt ID: O75948
PDB ID: None
Molecular Weight: 24 kDa
Subcellular Localization: Cytoplasm, Dendrites
Protein Family: Dynactin complex
DCTN3 has a distinctive structure adapted for its function:
DCTN3 (p24) is a subunit of the dynactin complex, which functions as a cofactor for dynein-mediated retrograde transport. It contributes to the structural integrity of the complex and participates in organelle transport, mitosis, and neuronal function.
DCTN3 is involved in neurodegenerative disorders. The dynactin complex dysfunction leads to impaired axonal transport in ALS, Perry syndrome, and Charcot-Marie-Tooth disease.
DCTN3 represents a potential therapeutic target:
Dctn3 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Dctn3 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.