| LRP1B Protein | |
|---|---|
| Name | Low Density Lipoprotein Receptor-Related Protein 1B |
| UniProt | Q9NZR2 |
| Gene | LRP1B |
| Molecular Weight | ~510 kDa |
| Length | 4,595 amino acids |
| Cellular Location | Plasma membrane |
| Expression | Brain, Lung, Kidney, Testis |
Lrp1B Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
LRP1B (Low Density Lipoprotein Receptor-Related Protein 1B) is a member of the LDLR family. It functions as a scavenger receptor involved in endocytosis of various ligands, including lipoproteins and extracellular matrix proteins.
LRP1B contains:
LRP1B participates in:
The study of Lrp1B Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
[1] Liu, C. et al. (2001). LRP1B, a novel candidate tumor suppressor gene. JBC, 276(38), 35589-35597.