.infobox .infobox-gene {
background-color: #f8f9fa;
border: 1px solid #ddd;
padding: 10px;
width: 300px;
font-size: 0.9em;
}
.infobox .infobox-gene .gene-symbol {
font-weight: bold;
font-size: 1.2em;
color: #2c5282;
}
.infobox .infobox-gene .gene-name {
font-style: italic;
margin-bottom: 10px;
}
.infobox .infobox-gene table {
width: 100%;
border-collapse: collapse;
}
.infobox .infobox-gene td {
padding: 4px;
vertical-align: top;
}
.infobox .infobox-gene td.label {
font-weight: bold;
width: 40%;
color: #555;
}
.infobox .infobox-gene td.value {
width: 60%;
}
.infobox .infobox-gene a {
color: #0066cc;
text-decoration: none;
}
.infobox .infobox-gene a:hover {
text-decoration: underline;
}
| Symbol | TRPC6 |
| Full Name | Transient Receptor Potential Cation Channel Subfamily C Member 6 |
| Chromosome | 11q22.1 |
| NCBI Gene | 7225 |
| OMIM | 602606 |
| Ensembl | ENSG00000137672 |
| UniProt | Q9Y5Q1 |
| Associated Diseases | FSGS, neuroprotection |
TRPC6 is a gene encoding a transient receptor potential (TRP) channel that plays important roles in sensory transduction and has been implicated in neurodegenerative diseases.
The TRPC6 gene encodes a non-selective cation channel belonging to the TRP superfamily. These channels are activated by various stimuli including temperature, chemicals, and mechanical force, and contribute to cellular calcium signaling.
TRP channels are widely expressed in the nervous system and participate in sensory perception, neuroprotection, and disease processes. The TRPC6 channel has been studied in the context of oxidative stress, neuroinflammation, and neurodegenerative conditions including Alzheimer's and Parkinson's disease.
TRPC6 is a mechanosensitive and receptor-operated calcium channel. It is expressed in the brain and contributes to neuronal excitability and dendritic spine morphology.
TRPC6 is a calcium-permeable channel involved in neuronal survival and synaptic plasticity.
Expressed in kidney and brain.