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| Symbol | TRPC3 |
| Full Name | Transient Receptor Potential Cation Channel Subfamily C Member 3 |
| Chromosome | 4q27 |
| NCBI Gene | 7222 |
| OMIM | 602444 |
| Ensembl | ENSG00000138741 |
| UniProt | Q9UQC2 |
| Associated Diseases | Ataxia, synaptic plasticity |
TRPC3 is a gene encoding a transient receptor potential (TRP) channel that plays important roles in sensory transduction and has been implicated in neurodegenerative diseases.
The TRPC3 gene encodes a non-selective cation channel belonging to the TRP superfamily. These channels are activated by various stimuli including temperature, chemicals, and mechanical force, and contribute to cellular calcium signaling.
TRP channels are widely expressed in the nervous system and participate in sensory perception, neuroprotection, and disease processes. The TRPC3 channel has been studied in the context of oxidative stress, neuroinflammation, and neurodegenerative conditions including Alzheimer's and Parkinson's disease.
TRPC3 is a member of the transient receptor potential canonical channel family. It is a non-selective cation channel involved in store-operated calcium entry and neuronal signaling.
TRPC3 is a non-selective cation channel involved in synaptic plasticity and motor coordination.
High expression in cerebellum.