Fzd10 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| FZD10 Gene | |
|---|---|
| Frizzled Class Receptor 10 | |
| Symbol | FZD10 |
| Full Name | Frizzled Class Receptor 10 |
| Chromosome | 12q14.1 |
| NCBI Gene ID | 8372 |
| Ensembl ID | ENSG00000111432 |
| OMIM ID | 605548 |
| UniProt ID | Q9ULW2 |
| Associated Diseases | Cancer, Synovial Sarcoma |
FZD10 (Frizzled Class Receptor 10) is a seven-transmembrane receptor that activates both canonical and non-canonical Wnt signaling pathways. It plays important roles in embryonic development, tissue patterning, and is frequently overexpressed in various cancers. FZD10 is predominantly expressed during development and at lower levels in adult tissues.
FZD10 activates multiple Wnt pathways:
FZD10 in development:
FZD10 modulates:
FZD10 frequently overexpressed in:
Potential associations with:
FZD10 is expressed in:
FZD10 interacts with:
FZD10-based approaches:
The study of Fzd10 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.