Fbxo3 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Protein Name | F-box Only Protein 3 |
|---|---|
| Gene | FBXO3 |
| UniProt ID | Q9UK81 |
| Molecular Weight | 52.0 kDa |
| Subcellular Localization | Cytoplasm |
| Protein Family | F-box protein family, SCF complex |
FBXO3 is an F-box protein component of SCF ubiquitin ligase complexes:
FBXO3 is part of the SCF (Skp1-Cul1-F-box) ubiquitin ligase complex:
Primary functions:
Liu J, et al. (2013). "F-box proteins in neurodegenerative diseases." Prog Neuropsychopharmacol Biol Psychiatry. 45:70-78.
Nelson RE, et al. (2011). "F-box proteins in neurodegenerative disease." Cell. 145(5):647-650.
The study of Fbxo3 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
FBXO3 encodes an F-box protein involved in ubiquitination and protein degradation. Associated with inflammatory responses and neurodegeneration.