Dynamin 3 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Dynamin 3 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Protein Name | Dynamin-3 |
| Gene | DNM3 |
| UniProt ID | Q9UQ16 |
| PDB Structures | 4UIM |
| Molecular Weight | 91 kDa |
| Subcellular Localization | Dendritic Spines, Postsynaptic Density |
| Protein Family | Dynamin family |
Dynamin-3 has unique N-terminal sequences compared to dynamin-1 and 2. It contains the characteristic GTPase, middle, and GED domains. Dynamin-3 has a distinct isoform pattern generated by alternative splicing. The protein localizes specifically to postsynaptic compartments.
Dynamin-3 is specifically involved in:
Dynamin-3 functions primarily in the postsynaptic compartment, distinct from the presynaptic function of dynamin-1.
Dynamin 3 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Dynamin 3 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.