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| Symbol | NCX2 |
| Full Name | Sodium Calcium Exchanger 2 |
| Chromosome | 15q21.3 |
| NCBI Gene | 6577 |
| OMIM | 607857 |
| Ensembl | ENSG00000126860 |
| UniProt | P55685 |
| Associated Diseases | Neuroprotection |
NCX2 is a gene encoding a protein involved in ion transport that plays important roles in neuronal function and has been implicated in neurodegenerative diseases.
The NCX2 gene encodes a protein that is part of a family of ion transporters critical for maintaining ionic homeostasis in neurons. These proteins are essential for proper neuronal excitability, calcium signaling, and cellular viability.
Ion transporters maintain the electrochemical gradients necessary for neuronal function. The NCX2 protein contributes to cellular homeostasis and has been studied in the context of excitotoxicity, calcium dysregulation, and neurodegenerative processes in Alzheimer's and Parkinson's disease.
NCX2 (SLC8A2) encodes sodium-calcium exchanger 2, primarily expressed in the brain. It plays important roles in neuronal calcium regulation and is implicated in excitotoxicity and neurodegeneration.
NCX2 is a sodium-calcium exchanger with neuronal expression. May have neuroprotective roles.
Expressed in brain.