Ms4A1 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| MS4A1 | |
|---|---|
| Gene Symbol | MS4A1 |
| Full Name | Membrane Spanning 4-Domains A1 (CD20) |
| Chromosomal Location | 11q12.2 |
| NCBI Gene ID | 931 |
| OMIM ID | 112210 |
| Ensembl ID | ENSG00000156738 |
| UniProt ID | P08581 |
| Encoded Protein | CD20 |
| Associated Diseases | Alzheimer's Disease, Multiple Sclerosis |
MS4A1 encodes CD20, a cell surface glycoprotein expressed primarily on B cells. It plays a role in B cell activation, proliferation, and calcium influx.
Key functions:
MS4A1 is expressed in:
The study of Ms4A1 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.