Anxiety disorders are a group of conditions marked by excessive fear, worry, and autonomic hyperarousal that impair daily function.[1][2] In NeuroWiki they appear most often as linked outcomes from amygdala, BNST, serotonergic, and stress-axis circuitry pages.
Anxiety disorders are associated with altered amygdala and extended-amygdala processing, dysregulated stress signaling, and abnormal serotonergic and noradrenergic modulation.[1:1][2:1] This makes them a useful translational anchor for pages on fear conditioning, hypothalamic-pituitary-adrenal axis, and ssri-antidepressants.
Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. Psychiatry Research: Neuroimaging (2007). ↩︎ ↩︎
The role of the central nucleus of the amygdala in fear and anxiety. Behavioural Brain Research (1994). ↩︎ ↩︎