Selective serotonin reuptake inhibitors (SSRIs) are antidepressants that increase synaptic serotonin by inhibiting the serotonin transporter.[1][2] In NeuroWiki they are commonly referenced from serotonergic, mood, and neuropsychiatric symptom pages.
SSRIs are important because they connect serotonergic circuit biology with treatment of depression and anxiety symptoms that often accompany neurologic disease.[1:1][2:1] They are also relevant to pages discussing serotonin-syndrome risk and neuropsychiatric management in neurodegeneration.
Serotonin in Parkinson's disease. Parkinsonism & Related Disorders (2015). ↩︎ ↩︎
Post-traumatic Stress Disorder: A Narrative Review of Pharmacological and Psychotherapeutic Interventions. Cureus (2023). ↩︎ ↩︎