Neural Stem Cell Therapy For Neurodegenerative Diseases is a treatment approach for neurodegenerative diseases. This page provides comprehensive information about its mechanism of action, clinical evidence, and therapeutic potential.
Neural stem cell (NSC) therapy represents a promising regenerative approach for neurodegenerative diseases. NSCs are multipotent progenitor cells capable of differentiating into neurons, astrocytes, and oligodendrocytes. They offer potential for replacing lost neurons, supporting surviving cells, and modulating the disease microenvironment. [1]
| Trial | Phase | Condition | Cell Type | Status | [2]
|-------|-------|-----------|-----------|--------| [3]
| NCT03724136 | I/II | PD | ESC-derived | Recruiting | [4]
| NCT04802733 | I | HD | Fetal-derived | Completed |
| NCT03714355 | I | ALS | NSC | Active |
| NCT03296656 | I | Stroke | NSC | Completed |
The study of Neural Stem Cell Therapy For Neurodegenerative Diseases has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Takahashi J. Stem cells and regenerative medicine for Parkinson's disease. 2020. ↩︎
Glass JD, et al. Neural stem cell transplantation in ALS: a Phase I trial. 2020. ↩︎
Kondziolka D, et al. Neuronal transplantation for stroke. 2021. ↩︎
Yuan T, et al. Induced neural stem cells for neurodegenerative disease treatment. 2022. ↩︎