Pablo G. Martinez is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Pablo G. Martinez is a leading researcher in the field of neurodegenerative diseases, affiliated with University of Barcelona [1]. Their research focuses on neuroinflammation, with particular emphasis on Alzheimer's Disease [2]. With an h-index of 60, Martinez is among the most cited researchers in the neuroscience field [3]. Martinez's work spans multiple aspects of neurodegeneration, contributing to our understanding of the molecular mechanisms that underlie diseases such as Alzheimer's Disease. Their research group has made significant contributions to the fields of neuroinflammation, publishing in high-impact journals including leading neuroscience journals. Based at University of Barcelona, Martinez collaborates with researchers across multiple institutions worldwide, working to advance therapeutic strategies for neurodegenerative conditions.
- [Alzheimer's disease[/diseases/[alzheimers[/diseases/[alzheimers[/diseases/[alzheimers--TEMP--/diseases)--FIX--
- [neuroinflammation[/mechanisms/[neuroinflammation[/mechanisms/[neuroinflammation[/mechanisms/[neuroinflammation--TEMP--/mechanisms)--FIX--
- [Researchers and Institutions Index[/[researchers[/[researchers[/[researchers[/[researchers[/[researchers[/researchers
- [Diseases Index[/[diseases[/[diseases[/[diseases[/[diseases[/[diseases[/diseases
- [Mechanisms Index[/[mechanisms[/[mechanisms[/[mechanisms[/[mechanisms[/[mechanisms[/mechanisms
Page auto-generated from NeuroWiki researcher database. Last updated: 2026-02-26.
The study of Pablo G. Martinez has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
- [Moutinho M et al.. "The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's Disease." Science translational medicine (2022). [DOI: 10.1126/scitranslmed.abl7634]https://doi.org/10.1126/scitranslmed.abl7634) PubMed: 35320002
- [Jury-Garfe N et al.. "Enhanced microglial dynamics and a paucity of [tau[/entities/[tau-protein[/entities/[tau-protein[/entities/[tau-protein--TEMP--/entities)--FIX-- seeding in the amyloid plaque microenvironment contribute to cognitive resilience in Alzheimer's Disease." Acta neuropathologica (2024). [DOI: 10.1007/s00401-024-02775-1]https://doi.org/10.1007/s00401-024-02775-1) PubMed: 39102080
- [Sanz-Moreno A et al.. "Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenita." Science advances (2025). [DOI: 10.1126/sciadv.adp8093]https://doi.org/10.1126/sciadv.adp8093) PubMed: 40215293
- [Martinez P et al.. "Bassoon contributes to tau-seed propagation and neurotoxicity." Nature neuroscience (2022). [DOI: 10.1038/s41593-022-01191-6]https://doi.org/10.1038/s41593-022-01191-6) PubMed: 36344699
- [Moutinho M et al.. "[TREM2[/entities/[trem2[/entities/[trem2[/entities/[trem2--TEMP--/entities)--FIX-- splice isoforms generate soluble TREM2 species that disrupt long-term potentiation." Genome medicine (2023). [DOI: 10.1186/s13073-023-01160-z]https://doi.org/10.1186/s13073-023-01160-z) PubMed: 36805764
- [Cisternas P et al.. "The reduction of astrocytic tau prevents amyloid-β-induced synaptotoxicity." Brain communications (2022). [DOI: 10.1093/braincomms/fcac235]https://doi.org/10.1093/braincomms/fcac235) PubMed: 36196088
- [Portacolone E et al.. "The Living Alone with Cognitive Impairment Project's Policy Advisory Group on Long-Term Services and Supports: Setting a Research Equity Agenda." Int J Environ Res Public Health (2022). [DOI: 10.3390/ijerph19106021]https://doi.org/10.3390/ijerph19106021) PubMed: 35627558
- [Martinez P et al.. "Protocol for the isolation and proteomic analysis of pathological tau-seeds." STAR protocols (2024). [DOI: 10.1016/j.xpro.2024.103185]https://doi.org/10.1016/j.xpro.2024.103185) PubMed: 39078738## Collaborators and Research Network
- Collaborator network pending enrichment.