Vti1B Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| VTI1B Protein | |
|---|---|
| Protein Name | Vesicle transport through interaction with t-SNAREs 1B |
| Alternative Names | VTI1B, Vti1-like 1B |
| UniProt ID | Q9UEU0 |
| Gene Symbol | VTI1B |
| Protein Type | v-SNARE protein |
| Molecular Weight | ~23 kDa (193 aa) |
| Cellular Location | Endosomal membranes, Lysosomal membranes |
This page provides comprehensive information about the subject's role in neurodegenerative diseases. The subject participates in various molecular pathways and cellular processes relevant to Alzheimer's disease, Parkinson's disease, and related conditions.
VTI1B is a SNARE protein containing:
VTI1B mediates membrane fusion as a v-SNARE:
| Partner | Interaction Type | Functional Significance |
|---|---|---|
| STX7 | t-SNARE | Late endosome fusion |
| STX8 | t-SNARE | Endolysosomal fusion |
| VAMP7/VAMP8 | v-SNARE | Lysosomal fusion |
The study of Vti1B Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.