Rabep1 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Rabaptin-5 Protein | |
|---|---|
| Protein Name | Rabaptin-5 |
| Alternative Names | RABEP1, Rabaptin |
| UniProt ID | Q9UNL2 |
| Gene Symbol | RABEP1 |
| Protein Type | Rab GTPase effector |
| Molecular Weight | ~130 kDa (1,178 aa) |
| Cellular Location | Cytoplasmic, Endosomal membranes |
This page provides comprehensive information about the subject's role in neurodegenerative diseases. The subject participates in various molecular pathways and cellular processes relevant to Alzheimer's disease, Parkinson's disease, and related conditions.
Rabaptin-5 is a large coiled-coil protein containing multiple:
As a Rab effector, Rabaptin-5 functions in:
| Partner | Interaction Type | Functional Significance |
|---|---|---|
| RAB5A | Direct binding | Early endosome fusion |
| RAB4A | Direct binding | Recycling endosomes |
| RAB11A | Direct binding | Recycling endosomes |
| RAB7A | Direct binding | Late endosome function |
The study of Rabep1 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.