Ndufs7 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Ndufs7 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
NDUFS7 Protein
| Protein Name | NDUFS7 Protein |
| Gene | NDUFS7 |
| UniProt ID | Q9Y5J9 |
| PDB IDs | 6RCQ, 6G72 |
| Molecular Weight | 20 kDa |
| Subcellular Localization | Mitochondrial Inner Membrane |
| Protein Family | NADH Dehydrogenase Complex I Subunits |
NDUFS7 protein belongs to the NADH Dehydrogenase Complex I Subunits. The protein localizes to Mitochondrial Inner Membrane.
NDUFS7 is a core subunit of mitochondrial Complex I involved in electron transfer from Fe-S clusters to ubiquinone.
NDUFS7 mutations cause mitochondrial Complex I deficiency and Leigh syndrome. Complex I dysfunction contributes to Parkinson's disease pathogenesis.
Treatment is supportive; CoQ10 and L-carnitine may provide some benefit.
Ndufs7 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Ndufs7 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.