Fam126A Protein (Family With Sequence Similarity 126 Member A) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
:: infobox .infobox-protein
| FAM126A Protein (Family with Sequence Similarity 126 Member A) | |
|---|---|
| Gene | FAM126A |
| UniProt | Q9BYH3 |
| Molecular Weight | ~27 kDa |
| Subcellular Localization | Plasma membrane, myelin sheaths |
| Protein Family | FAM126 family |
| Aliases | FAM126A, DRCTNNB1A, Hyccin |
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FAM126A (Family with Sequence Similarity 126 Member A) is a protein involved in various cellular processes. This protein plays important roles in cellular signaling and function.
FAM126A (also known as Hyccin) is a membrane-associated protein. The protein is approximately 246 amino acids and is expressed in oligodendrocytes and Schwann cells, where it localizes to the plasma membrane and myelin sheaths.
FAM126A is essential for:
FAM126A mutations cause familial hypomagnesemia with neurological symptoms:
FAM126A expression is altered in MS lesions:
FAM126A-related leukodystrophy involves white matter abnormalities.
FAM126A-based therapies target:
The study of Fam126A Protein (Family With Sequence Similarity 126 Member A) has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.