Epha4 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Epha4 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Eph Receptor A4 | |
|---|---|
| Protein Name | Eph Receptor A4 |
| Gene | EPHA4 |
| UniProt ID | Q06432 |
| PDB ID | 2RBP |
| Molecular Weight | 110 kDa |
| Subcellular Location | Plasma membrane |
| Protein Family | Eph receptor family |
Eph Receptor A4 is a Eph receptor family protein with characteristic structural features.
EphA4 is a receptor tyrosine kinase that binds ephrin ligands. It regulates synaptic function, spine morphology, and excitatory neurotransmission.
Alzheimer's Disease - EphA4 is upregulated in AD and affects synaptic plasticity. ALS - EphA4 mediates motor neuron degeneration.
Epha4 Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Epha4 Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.