C Rel Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
C Rel Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| c-Rel Protein | |
|---|---|
| Protein Name | c-Rel Protein |
| Gene | REL |
| UniProt ID | P41160 |
| PDB IDs | 1GJF, 2LGG |
| Molecular Weight | 68 kDa |
| Subcellular Location | Nucleus |
| Protein Family | NF-κB transcription factors |
c-Rel Protein is a NF-κB transcription factors. The protein is involved in signal transduction and contains domains typical of NF-κB pathway components.
c-Rel is a NF-κB family member that forms dimers with p50 and p52. It regulates genes involved in immune cell activation, proliferation, and survival. c-Rel is essential for B cell function, T cell development, and macrophage activation.
c-Rel is overexpressed in B cell lymphomas. Altered c-Rel signaling may contribute to inflammatory diseases.
Experimental c-Rel inhibitors under development.
C Rel Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of C Rel Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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