Complexin 1 Protein (Cplx1) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
The CPLX1 gene encodes Complexin-1, a SNARE complex regulator.
{{infobox .infobox-protein
|title=Complexin-1 Protein
|gene=CPLX1
|uniprot=O75178
|pdb=1K5J, 2N0P
|molecular_weight=15 kDa
|localization=Presynaptic terminal
|family=Complexin family
}}
COMPLEXIN 1 PROTEIN is a gene/protein encoding a key neuronal protein involved in synaptic function, signal transduction, and cellular homeostasis. Dysfunction of COMPLEXIN 1 PROTEIN is associated with neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, and related disorders.
Complexin-1 is a small soluble protein with:
The study of Complexin 1 Protein (Cplx1) has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.