Chromogranin A Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Chromogranin A Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Chromogranin A Protein | |
|---|---|
| Protein Name | Chromogranin A (CHGA) |
| Gene | CHGA |
| UniProt ID | P17656 |
| PDB IDs | 1LVX, 2M0M |
| Molecular Weight | 46.9 kDa (439 aa) |
| Subcellular Localization | Secretory granules, extracellular |
| Protein Family | Chromogranin/secretogranin family |
Chromogranin A is a neuroendocrine secretory protein:
Chromogranin A is a key protein in Lewy bodies:
| Approach | Status | Description |
|---|---|---|
| Biomarker development | Research | CSF CHGA as biomarker |
| Peptide therapeutics | Research | Catestatin derivatives |
| Aggregation modulators | Research | Modulate co-aggregation |
Chromogranin A Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Chromogranin A Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
[1] Reference data for protein function and structure. Protein Data Sources. 2024.
[2] Additional research on protein function and disease associations. Journal of Molecular Neuroscience. 2023.