CHL1 (CHL1/L1.2) is a cell adhesion molecule of the L1 family. It mediates homophilic and heterophilic cell-cell adhesion in the nervous system. CHL1 is important for neuronal development, migration, and synaptic plasticity.
| Attribute | Value |
|---|---|
| Protein Name | Cell Adhesion Molecule L1-Like |
| Gene | CHL1 |
| UniProt ID | O43322 |
| PDB ID | N/A |
| Molecular Weight | 186 kDa |
| Subcellular Localization | Plasma membrane |
| Protein Family | Immunoglobulin superfamily |
Cell Adhesion Molecule L1-Like is a Immunoglobulin superfamily protein involved in various cellular processes in the nervous system.
CHL1 (CHL1/L1.2) is a cell adhesion molecule of the L1 family. It mediates homophilic and heterophilic cell-cell adhesion in the nervous system. CHL1 is important for neuronal development, migration, and synaptic plasticity.
CHL1 mutations or dysregulation may contribute to neurodevelopmental and neurodegenerative conditions.
Research ongoing to understand CHL1-based therapies.