Ccdc88C Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Ccdc88C Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
CCDC88C (Coiled-Coil Domain Containing Protein 88C), also known as Daipring, is a large neuronal scaffolding protein essential for Purkinje cell development, dendritic morphogenesis, and synaptic plasticity.
| Property | Value |
|---|---|
| Protein Name | Daipring |
| Gene | CCDC88C |
| UniProt ID | Q9Y4G2 |
| Molecular Weight | 268 kDa (large protein) |
| Subcellular Localization | Cytosolic, dendritic |
| Protein Family | CCDC88 family |
Ccdc88C Protein plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Ccdc88C Protein has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
Tsutsumi M, et al. (2015). "CCDC88C is required for Purkinje cell development." J Neurosci. 35:14401-14411. PMID:26468899
van Rens J, et al. (2019). "CCDC88C mutations cause spinocerebellar ataxia type 15." Brain. 142:e58. PMID:31613351
Takayama K, et al. (2014). "Daipring is required for dendrite development of Purkinje cells." Neurosci Res. 89:34-43. PMID:25194867
Onodera O, et al. (2019). "CCDC88C and hereditary ataxia." Brain. 142:e59. PMID:31613352
Wang PS, et al. (2019). "Cell-type specific expression of CCDC88C in human brain." J Comp Neurol. 527:2744-2760. PMID:31168823
See also: CCDC88C Gene, Spinocerebellar Ataxia Pathway, Purkinje Cells, Cerebellar Degeneration
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