AQP1 is a water channel that facilitates rapid water transport across cell membranes. In the brain, it is expressed in choroid plexus and contributes to CSF production. AQP1 may participate in brain water homeostasis.
| Attribute | Value |
|---|---|
| Protein Name | Aquaporin-1 |
| Gene | AQP1 |
| UniProt ID | P29972 |
| PDB ID | 1J4N |
| Molecular Weight | 28 kDa |
| Subcellular Localization | Plasma membrane |
| Protein Family | Aquaporin family |
Aquaporin-1 is a Aquaporin family protein involved in various cellular processes in the nervous system.
AQP1 is a water channel that facilitates rapid water transport across cell membranes. In the brain, it is expressed in choroid plexus and contributes to CSF production. AQP1 may participate in brain water homeostasis.
AQP1 expression may be altered in various neurological conditions affecting water balance.
Aquaporin modulators are being developed for edema and other conditions.