ADORA2B encodes the adenosine A2b receptor, a G protein-coupled receptor that stimulates adenylate cyclase. It is expressed at lower levels than A2A and is induced during inflammation. A2B receptors may modulate neuroinflammation and glial responses.
| Attribute | Value |
|---|---|
| Protein Name | Adenosine A2b Receptor |
| Gene | ADORA2B |
| UniProt ID | P29274 |
| PDB ID | 3OCC |
| Molecular Weight | 44 kDa |
| Subcellular Localization | Plasma membrane |
| Protein Family | G protein-coupled receptor, Adenosine receptor family |
Adenosine A2b Receptor is a G protein-coupled receptor, Adenosine receptor family protein involved in neuroprotection and neuronal function.
ADORA2B encodes the adenosine A2b receptor, a G protein-coupled receptor that stimulates adenylate cyclase. It is expressed at lower levels than A2A and is induced during inflammation. A2B receptors may modulate neuroinflammation and glial responses.
A2B receptors may play roles in chronic inflammation and neurodegenerative processes.
A2B receptor antagonists are being explored for inflammatory conditions.