TRIM55 (MURF-2) is a muscle-specific E3 ubiquitin ligase involved in muscle protein degradation and sarcomere maintenance. It interacts with troponin and myosin binding proteins.
| Property | Value |
|---|---|
| Gene Symbol | TRIM55 |
| Gene Name | Tripartite Motif Containing 55 (MURF-2) |
| Chromosomal Location | 8q24.13 |
| NCBI Gene ID | 80316 |
| OMIM | 608598 |
| UniProt | Q9C0B1 |
TRIM55 (MURF-2) is a muscle-specific E3 ubiquitin ligase involved in muscle protein degradation and sarcomere maintenance. It interacts with troponin and myosin binding proteins.
The TRIM55 gene is associated with the following neurodegenerative and related diseases:
TRIM55 expression and its relevance to brain function is under active investigation.