TRIM25 is an E3 ubiquitin ligase that functions in innate immunity and has been implicated in Parkinson's disease. It is involved in mitochondrial quality control and the regulation of mitophagy.
| Property | Value |
|---|---|
| Gene Symbol | TRIM25 |
| Gene Name | Tripartite Motif Containing 25 |
| Chromosomal Location | 17q11.2 |
| NCBI Gene ID | 11067 |
| OMIM | 606112 |
| UniProt | Q9C0B1 |
TRIM25 is an E3 ubiquitin ligase that functions in innate immunity and has been implicated in Parkinson's disease. It is involved in mitochondrial quality control and the regulation of mitophagy.
The TRIM25 gene is associated with the following neurodegenerative and related diseases:
TRIM25 expression and its relevance to brain function is under active investigation.