Sptlc2 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
SPTLC2 (Serine Palmitoyltransferase Long Chain Base Subunit 2) encodes the small subunit of serine palmitoyltransferase. It is implicated in hereditary sensory neuropathy and Alzheimer's disease.
| Attribute | Value |
|---|---|
| Gene Symbol | SPTLC2 |
| Full Name | Serine Palmitoyltransferase Long Chain Base Subunit 2 |
| Chromosomal Location | 14q31.3 |
| NCBI Gene ID | 9517 |
| Ensembl ID | ENSG00000166800 |
| UniProt ID | O15270 |
| OMIM | 610313 |
SPTLC2 is the small subunit of serine palmitoyltransferase (SPT):
Essential for production of:
HSAN1B (OMIM 613640):
SPTLC2 is ubiquitously expressed:
The study of Sptlc2 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.