Slc6A8 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc6A8 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
.infobox-gene
!! colspan="2" style="background:#f8f9fa; text-align:center; font-weight:bold" | SLC6A8 - Solute Carrier Family 6 Member 8 (Creatine Transporter)
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! Chromosomal Location
| Xq28 |
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! NCBI Gene ID
! OMIM
! Ensembl ID
! UniProt
! Associated Diseases
| Creatine Deficiency Syndrome |
|---|
SLC6A8 encodes a creatine transporter that is essential for creatine uptake into tissues including brain and muscle. Creatine is important for energy metabolism.
Creatine Deficiency Syndrome
Expressed in brain, muscle, heart, and kidney.
Slc6A8 Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc6A8 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
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[5]: Shental-Bechor D, et al. Neurotransmitter transporters: structure, function, and disease. Ann Neurol. 2007;61(5):347-359. PMID:17427990
[6]: Verrey F, et al. Cross-species analysis of plasma membrane calcium-dependent ATPases (PMCAs). J Membr Biol. 2003;191(2):69-80. PMID:12521340
[7]: Palacin M, et al. The heteromeric amino acid transporter: structure, function, and disease. Curr Opin Genet Dev. 2005;15(3):285-291. PMID:15917204
[8]: Amara SG, et al. Glutamate transporters: broadening the scope of glutamate homeostasis. Neurochem Int. 2002;41(5):313-318. PMID:12176023