Slc39A8 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc39A8 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Solute Carrier Family 39 Member 8 | |
|---|---|
| Gene Symbol | SLC39A8 |
| Full Name | Solute Carrier Family 39 Member 8 |
| Chromosome | 4q24 |
| NCBI Gene ID | 64116 |
| OMIM | 608732 |
| Ensembl ID | ENSG00000138821 |
| UniProt ID | Q9C0K1 |
| Associated Diseases | Parkinson's Disease, Leigh Syndrome, Congenital Disorder of Glycosylation |
SLC39A8 (Zip8) encodes a zinc and iron transporter. It is involved in metal homeostasis and is implicated in neurodegeneration through its role in metal transport across the blood-brain barrier.
Broad expression, high in kidney, liver, and brain.
| Disease | Variants | Inheritance | Mechanism |
|---|---|---|---|
| Parkinson's Disease | Various | Variable | Altered function |
Slc39A8 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc39A8 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.