Slc11A1 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Slc11A1 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Solute Carrier Family 11 Member 1 | |
|---|---|
| Gene Symbol | SLC11A1 |
| Full Name | Solute Carrier Family 11 Member 1 |
| Chromosome | 2q35 |
| NCBI Gene ID | 6556 |
| OMIM | 604253 |
| Ensembl ID | ENSG00000008080 |
| UniProt ID | P78609 |
| Associated Diseases | Parkinson's Disease, Infectious Disease Susceptibility |
SLC11A1 (NRAMP1) is a divalent metal transporter involved in iron and manganese transport. It is expressed in microglia and macrophages and modulates neuroinflammation.
High in macrophages, microglia, and neutrophils.
| Disease | Variants | Inheritance | Mechanism |
|---|---|---|---|
| Parkinson's Disease | Various | Variable | Altered function |
Slc11A1 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Slc11A1 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.