RORC Gene is involved in circadian rhythm regulation and has been implicated in neurodegenerative diseases. This page provides information about its structure, function, and role in neurodegeneration.
RORC Gene plays a critical role in the molecular circadian clock and its dysregulation may contribute to neurodegeneration.
| RORC — RAR Related Orphan Receptor C | |
|---|---|
| Gene Symbol | RORC |
| Full Name | RORC — RAR Related Orphan Receptor C |
| Chromosome | 1q21.2 |
| NCBI Gene ID | 5873 |
| OMIM | 607037 |
| Ensembl ID | ENSG00000143357 |
| UniProt ID | P51586 |
| Associated Diseases | Metabolic disorders, immune disorders |
RORC (RORγ) is a nuclear receptor that drives circadian gene expression. RORC regulates genes involved in metabolism, immunity, and development.
RORC modulates neuroinflammation and may be relevant to neurodegenerative disease pathogenesis.
Expressed in thymus, liver, and various tissues. Lower expression in brain.