RORA Gene is involved in circadian rhythm regulation and has been implicated in neurodegenerative diseases. This page provides information about its structure, function, and role in neurodegeneration.
RORA Gene plays a critical role in the molecular circadian clock and its dysregulation may contribute to neurodegeneration.
| RORA — RAR Related Orphan Receptor A | |
|---|---|
| Gene Symbol | RORA |
| Full Name | RORA — RAR Related Orphan Receptor A |
| Chromosome | 15q22.2 |
| NCBI Gene ID | 6015 |
| OMIM | 600825 |
| Ensembl ID | ENSG00000069667 |
| UniProt ID | Q9Y5X4 |
| Associated Diseases | Ataxia, neurodegeneration |
RORA is a nuclear receptor that regulates circadian rhythm genes. It is essential for cerebellar development.
RORA mutations cause ataxia in mice and may contribute to neurodegeneration in humans.
Expressed in cerebellum, hippocampus, and other brain regions.