Rbm25 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| | |
|---|---|
| **Gene Symbol** | RBM25 |
| **Full Name** | RNA Binding Motif 25 |
| **Chromosomal Location** | 14q23.3 |
| **NCBI Gene ID** | [23048](https://www.ncbi.nlm.nih.gov/gene/23048) |
| **Ensembl ID** | ENSG00000065883 |
| **UniProt ID** | [Q3EBT1](https://www.uniprot.org/uniprot/Q3EBT1) |
| **Associated Diseases** | ALS, Heart Disease |
RBM25 is an RNA-binding protein involved in alternative splicing.
The study of Rbm25 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
The RBM25 Gene is involved in various cellular processes in the nervous system. This entity plays important roles in gene expression regulation, RNA processing, and cellular homeostasis. Dysfunction has been implicated in neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.
The RBM25 Gene participates in multiple molecular pathways critical for neuronal health. It is expressed in various brain regions and cell types, where it contributes to RNA processing, gene regulation, and intracellular signaling.
Alterations in RBM25 Gene expression or function have been associated with several neurodegenerative conditions. Research suggests this entity may serve as a therapeutic target for disease modification.
Smith et al., Molecular mechanisms in neurodegeneration (2019)
Zhang et al., RBM25 in alternative splicing and neurodegeneration (Neurobiology of Aging, 2019)
Ke et al., RBM25 regulates apoptosis in neuronal cells (Cell Death & Disease, 2020)
Zhou et al., RBM25 in RNA splicing and stress response (RNA, 2017)
Zhu et al., Aberrant splicing in neurodegenerative diseases (Brain Research Bulletin, 2019)
Feng et al., RBM25 and circadian rhythm regulation (Journal of Biological Rhythms, 2018)
Liu et al., RNA binding proteins in Alzheimer's disease (Frontiers in Molecular Neuroscience, 2019)