MYH7 encodes the beta-myosin heavy chain, a motor protein expressed in cardiac and slow skeletal muscle. It is one of the most commonly mutated genes in hypertrophic cardiomyopathy and is also associated with dilated cardiomyopathy and myosin storage myopathy.
| Property | Value |
|---|---|
| Gene Symbol | MYH7 |
| Gene Name | Myosin Heavy Chain 7 (Beta-Myosin) |
| Chromosomal Location | 14q11.2 |
| NCBI Gene ID | 4625 |
| OMIM | 160760 |
| UniProt | P12883 |
MYH7 encodes the beta-myosin heavy chain, a motor protein expressed in cardiac and slow skeletal muscle. It is one of the most commonly mutated genes in hypertrophic cardiomyopathy and is also associated with dilated cardiomyopathy and myosin storage myopathy.
The MYH7 gene is associated with the following neurodegenerative and related diseases:
MYH7 expression and its relevance to brain function is under active investigation.