Ms4A6E Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
MS4A6E (Membrane Spanning 4-Domains A6E) is a gene located on chromosome 11q12.2 that plays a critical role in neurodegenerative disease. Mutations in MS4A6E are associated with Alzheimer'S Disease. The gene is catalogued as NCBI Gene ID 9315 and OMIM 606546.
See Ms4A6E Protein for detailed structural and functional information about the encoded protein.
The MS4A6E gene encodes a protein involved in various cellular processes in neurons. The protein localizes to specific cellular compartments and participates in key neuronal functions including synaptic transmission, membrane trafficking, and cellular homeostasis.
Expression data is available from the Allen Human Brain Atlas.
MS4A6E mutations are linked to the following neurodegenerative conditions:
The study of Ms4A6E Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.