Kif3A — Kinesin Family Member 3A is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| KIF3A | |
|---|---|
| Full Name | Kinesin Family Member 3A |
| Chromosome | 5q31.2 |
| NCBI Gene ID | 11128 |
| Ensembl ID | ENSG00000101290 |
| OMIM ID | 604527 |
| UniProt ID | Q9Y5R6 |
| Associated Diseases | Joubert Syndrome, Sonic Hedgehog signaling |
KIF3A (Kinesin Family Member 3A) is a gene involved in neuronal function and intracellular transport. The gene is located on chromosome 5q31.2.
KIF3A encodes a member of the kinesin family of proteins. Kinesins are motor proteins that transport cargo along microtubules, playing essential roles in intracellular organization, vesicle trafficking, and cell division.
Mutations in KIF3A are associated with several disorders:
The gene is primarily expressed in:
The study of Kif3A — Kinesin Family Member 3A has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.