Kcne5 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
KCNE5 modulates potassium channel function. It is expressed in the heart and brain. Mutations are associated with cardiac arrhythmia syndromes including Brugada syndrome.
KCNE5 (Potassium Voltage-Gated Channel Subfamily E Regulatory Subunit 5) is a gene located on chromosome Xq23 that plays an important role in neurodegenerative disease. Mutations in KCNE5 are associated with Cardiac Arrhythmia, Brugada Syndrome. The gene is catalogued as NCBI Gene ID 286058 and OMIM 300638.
The KCNE5 gene encodes a protein involved in key neuronal functions. It is expressed in Heart, Brain.
Expression data is available from the Allen Human Brain Atlas.
KCNE5 mutations are linked to the following conditions:
Cardiac Arrhythmia, Brugada Syndrome
The study of Kcne5 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.