KAT6B (Lysine Acetyltransferase 6B), also known as MORF or MYST4, is another member of the MYST family of histone acetyltransferases. It shares structural and functional similarity with KAT6A and plays important roles in development and disease.
| Property | Value |
|---|---|
| Gene Symbol | KAT6B |
| Gene Name | Lysine Acetyltransferase 6B |
| Aliases | MORF, MYST4, QKF |
| Chromosomal Location | 10q22.2 |
| NCBI Gene ID | 23522 |
| OMIM | 607528 |
| UniProt | Q9H0H5 |
| Ensembl | ENSG00000138311 |
KAT6B encodes a histone acetyltransferase with similar domain structure to KAT6A:
KAT6B interacts with:
KAT6B is essential for normal development:
Regulates gene expression in:
KAT6B mutations cause:
Related clinical features:
Less frequently involved than KAT6A, but:
KAT6B is a developmental histone acetyltransferase with roles in transcription and chromatin regulation. Mutations cause developmental syndromes.