Got1 Glutamic Oxaloacetic Transaminase 1 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Got1 Glutamic Oxaloacetic Transaminase 1 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Glutamic-Oxaloacetic Transaminase 1 | |
|---|---|
| Gene Symbol | GOT1 |
| Full Name | Glutamic-Oxaloacetic Transaminase 1 |
| Chromosome | 10q24.3 |
| NCBI Gene ID | 2805 |
| OMIM | 138150 |
| Ensembl ID | ENSG00000163283 |
| UniProt ID | P17174 |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, Liver Disease |
GOT1 (Aspartate Aminotransferase 1) is an enzyme that catalyzes the reversible transfer of amino groups between aspartate and glutamate. It is important for amino acid metabolism and the malate-aspartate shuttle[^1].
GOT1 is an aminotransferase:
GOT1 performs metabolic functions:
GOT1 may be implicated in AD:
GOT1 is expressed in:
In the brain, GOT1 is expressed in neurons and astrocytes.
Got1 Glutamic Oxaloacetic Transaminase 1 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Got1 Glutamic Oxaloacetic Transaminase 1 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.