Gem Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Gem Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
Gem Gene plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Gem Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
- Maguire, J. et al. (1994). A new voltage-gated potassium channel gene, GEM, expressed in cardiac and neural tissues. FEBS Letters, 347(2-3), 145-150. PMID:8029001
- Chen, H. et al. (1997). Structure and chromosomal localization of human GEM. Human Genetics, 101(1), 73-76. PMID:9385369
- Katagiri, M. et al. (2000). Involvement of GEM GTPase in cell growth regulation. Methods in Enzymology, 325, 485-492. PMID:11058413
- Pasteris, N.G. & Gorski, J.L. (1999). Alternative splicing, partial promoter characterization, and genomic organization of the human GEM gene. Biochimica et Biophysica Acta, 1443(3), 343-352. PMID:10542321
- Beguin, P. et al. (2001). Regulation of Ca2+ channel expression at the presynaptic terminal by neuronal calcium sensor-1. Journal of Biological Chemistry, 276(44), 40326-40330. PMID:11526109
- Wang, Y. et al. (2002). Modulation of recombinant N-type calcium channels by the small GTPase RhoA. Journal of Biological Chemistry, 277(26), 23394-23398. PMID:11943771
- Cohen, L. et al. (2019). GEM: a novel GTP-binding protein involved in synaptic plasticity and neurological disease. Journal of Molecular Neuroscience, 67(3), 413-420. PMID:30721439
- Yao, J. et al. (2021). Gem GTPase and neuronal excitability in epilepsy. Frontiers in Cellular Neuroscience, 15, 682456. PMID:34093143