Gas6 Growth Arrest Specific 6 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
Gas6 Growth Arrest Specific 6 is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Growth Arrest Specific 6 | |
|---|---|
| Gene Symbol | GAS6 |
| Full Name | Growth Arrest Specific 6 |
| Chromosome | 13q34 |
| NCBI Gene ID | 2621 |
| OMIM | 600441 |
| Ensembl ID | ENSG00000111321 |
| UniProt ID | P14384 |
| Associated Diseases | Alzheimer's Disease, Parkinson's Disease, Thrombosis, Cancer |
GAS6 (Growth Arrest-Specific 6) is a ligand for TAM receptors (TYRO3, AXL, MERTK). It mediates cell survival, proliferation, and phagocytic clearance[^1].
GAS6 is a TAM receptor ligand:
GAS6 performs multiple functions:
GAS6 is implicated in AD:
In PD:
GAS6 is expressed in:
In the brain, GAS6 is expressed by neurons and glia, supporting TAM receptor signaling.
Gas6 Growth Arrest Specific 6 plays an important role in the study of neurodegenerative diseases. This page provides comprehensive information about this topic, including its mechanisms, significance in disease processes, and therapeutic implications.
The study of Gas6 Growth Arrest Specific 6 has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.