Fancf Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Fanconi Anemia Group F | |
|---|---|
| Gene Symbol | FANCF |
| Full Name | Fanconi Anemia Group F |
| Chromosome | 11p15 |
| NCBI Gene ID | 63027 |
| OMIM | 600901 |
| Ensembl ID | ENSG00000163930 |
| UniProt ID | Q9NPI8 |
| Associated Diseases | Fanconi Anemia, Breast Cancer |
FANCF encodes a protein that acts as an adaptor within the FA core complex, stabilizing the complex and facilitating proper monoubiquitination of FANCD2.
FANCF is a key scaffold protein in the FA core complex.
Key functions include:
FANCF is expressed ubiquitously
The study of Fancf Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
FANCF is involved in the Fanconi anemia DNA repair pathway.