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| Symbol | EFNB1 |
| Full Name | Ephrin B1 |
| Chromosome | Xq12 |
| NCBI Gene | 1946 |
| OMIM | 300037 |
| Ensembl | ENSG00000190784 |
| UniProt | P98172 |
| Associated Diseases | Neurodevelopmental disorders, memory |
EFNB1 (Ephrin B1) is a transmembrane ligand for EPHB receptors that mediates cell-cell communication and regulates synaptic plasticity. As an ephrin family member, EFNB1 plays crucial roles in neural development, synaptic function, and cellular signaling. Altered EFNB1 expression has been implicated in neurodegenerative diseases, particularly Alzheimer's disease and Parkinson's disease.
EFNB1 is a transmembrane ephrin ligand for EPHB receptors. It mediates bidirectional signaling and regulates synaptic development, dendritic spine formation, and learning.
Expressed in hippocampus, cortex, and olfactory bulb.