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| Symbol | EFNA3 |
| Full Name | Ephrin A3 |
| Chromosome | 3q13.33 |
| NCBI Gene | 1944 |
| OMIM | 602019 |
| Ensembl | ENSG00000163407 |
| UniProt | P52797 |
| Associated Diseases | Neurodevelopment, synaptic plasticity |
EFNA3 (Ephrin A3) is a GPI-anchored ligand for EPHA receptors that mediates cell-cell communication and regulates synaptic plasticity. As an ephrin family member, EFNA3 plays crucial roles in neural development, synaptic function, and cellular signaling. Altered EFNA3 expression has been implicated in neurodegenerative diseases, particularly Alzheimer's disease, as well as in various cancers.
EFNA3 is an ephrin-A ligand that binds EPHA receptors. It participates in neural development, synaptic plasticity, and may have roles in neurodegeneration.
Expressed in developing and adult brain.