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| Symbol | EFNA2 |
| Full Name | Ephrin A2 |
| Chromosome | 19p13.3 |
| NCBI Gene | 1943 |
| OMIM | 596339 |
| Ensembl | ENSG00000146700 |
| UniProt | O43923 |
| Associated Diseases | CNS development, visual system |
EFNA2 (Ephrin A2) is a GPI-anchored ligand for EPHA receptors that mediates cell-cell communication and regulates synaptic plasticity. As an ephrin family member, EFNA2 plays crucial roles in neural development, synaptic function, and cellular signaling. Altered EFNA2 expression has been implicated in neurodegenerative diseases, particularly Alzheimer's disease, as well as in various cancers.
EFNA2 is an ephrin-A ligand that regulates EPHA receptor signaling. It plays important roles in neural circuit formation, particularly in the visual system.
Expressed in retina and brain.