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| Symbol | CHRNA3 |
| Full Name | Cholinergic Receptor Nicotinic Alpha Subunit 3 |
| Chromosome | 15q25.1 |
| NCBI Gene | 1136 |
| OMIM | 118505 |
| Ensembl | ENSG00000138028 |
| UniProt | P30531 |
| Associated Diseases | Lung cancer, cognitive function |
CHRNA3 (Cholinergic Receptor Nicotinic Alpha 3) is a nicotinic acetylcholine receptor subunit that forms ligand-gated ion channels. Nicotinic receptors are crucial for fast synaptic transmission and regulate neuronal excitability, cognitive function, and synaptic plasticity. CHRNA3 has been implicated in neurodegenerative diseases and addiction.
CHRNA3 encodes the alpha-3 subunit of nicotinic receptors. Important for autonomic function and addiction.
Expressed in autonomic ganglia and brain.