Cd59 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Gene Symbol | CD59 |
|---|---|
| Full Name | CD59 molecule |
| Chromosomal Location | 11p13 |
| NCBI Gene ID | [https://www.ncbi.nlm.nih.gov/gene/969 969] |
| OMIM | [https://www.omim.org/entry/107271 107271] |
| Ensembl ID | ENSG00000085059 |
| UniProt ID | [https://www.uniprot.org/uniprot/P13946 P13946] |
| Associated Diseases | [Multiple Sclerosis](/diseases/multiple-sclerosis), [Stroke](/diseases/stroke), [Alzheimer's Disease](/diseases/alzheimer-disease) |
CD59 is a complement regulatory protein that inhibits the formation of the membrane attack complex (MAC) by preventing the incorporation of C5b-8 and C5b-9 into the membrane.
CD59 is expressed on:
The study of Cd59 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.
The CD59 Gene is involved in various cellular processes in the nervous system. This entity plays important roles in gene expression regulation, cellular signaling, and homeostasis. Dysfunction has been implicated in neurodegenerative diseases including Alzheimer's disease, Parkinson's disease, and related disorders.
The CD59 Gene participates in multiple molecular pathways critical for neuronal health. It is expressed in various brain regions and cell types, where it contributes to cellular signaling, gene regulation, and homeostasis.
Alterations in CD59 Gene expression or function have been associated with several neurodegenerative conditions. Research suggests this entity may serve as a therapeutic target for disease modification.