Bai1 Gene is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Property | Value |
|---|---|
| Gene Symbol | BAI1 |
| Full Name | Brain Specific Angiogenesis Inhibitor 1 |
| Chromosomal Location | 8q24.12 |
| NCBI Gene ID | 575 |
| OMIM ID | 602680 |
| Ensembl ID | ENSG00000181789 |
| UniProt ID | O14514 |
| Encoded Protein | Brain-specific angiogenesis inhibitor 1 |
| Associated Diseases | Glioblastoma, neurodegeneration |
BAI1 is a gene involved in various cellular processes. The encoded protein plays important roles in metabolism, cellular signaling, and disease pathogenesis.
BAI1 encodes a brain-specific angiogenesis inhibitor that regulates vascularization in the brain and has important functions in synaptic plasticity and phagocytosis.
Key functions include:
BAI1 is frequently downregulated in glioblastoma and acts as a tumor suppressor.
BAI1 dysfunction may contribute to neurodegeneration through:
BAI1 is expressed in:
The study of Bai1 Gene has evolved significantly over the past decades. Research in this area has revealed important insights into the underlying mechanisms of neurodegeneration and continues to drive therapeutic development.
Historical context and key discoveries in this field have shaped our current understanding and will continue to guide future research directions.